Friday, April 10, 2020

About the Drosten Test (Dr. Wolfgang Wodarg)

More good questions by Dr. Wodarg (roughly translated from German):

A tiger in the New York zoo was recently infected by the zookeeper with SARS-CoV-2. How can a test supposedly detect the different SARS viruses of European bats (Drosten), dogs (Hong Kong), tigers (New York) and humans (worldwide) that have been changing and spreading worldwide for many years, are specifically named for the detection of a SARS-CoV-2 that is said to be only four months old?
The tests now used everywhere ("not approved for diagnostic purposes") are specific for SARS CoV X - B viruses and not validated as medical devices.
* X stands for the countless SARS-like corona viruses that have been widespread in many species and in humans worldwide for years.
* B names those in which the responsible virologists did not find the test sequences they were looking for with the PCR test.
The family tree of SARS-like viruses is certainly older than virology and it is probably not a tree either, but a network of mutually changing microorganisms that has been constantly changing for longer than there are humans due to the pressure to adapt to new immunities.
(Citing: https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2020.25.3.2000045)

Given the poor translation (I'm using Google Translate), Wodarg's argument is a little difficult to understand, but I think it goes something like this. The corona virus is nothing new (it must have been around for a long time).

NOTE: From the abstract of the above-cited study by C. Drosten et al., the following are the reported methods and results, which Dr. Wodarg disputes:
Methods: Here we present a validated diagnostic workflow for 2019-nCoV, its design relying on close genetic relatedness of 2019-nCoV with SARS coronavirus, making use of synthetic nucleic acid technology. 
Results: The workflow reliably detects 2019-nCoV, and further discriminates 2019-nCoV from SARS-CoV. Through coordination between academic and public laboratories, we confirmed assay exclusivity based on 297 original clinical specimens containing a full spectrum of human respiratory viruses. Control material is made available through European Virus Archive – Global (EVAg), a European Union infrastructure project.

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